Mesenchymal stem cells to treat diabetic neuropathy: a long and strenuous way from bench to the clinic

As one of the most common complications of diabetes, diabetic neuropathy often causes foot ulcers and even limb amputations. Inspite of continuous development in antidiabetic drugs, there is still no efficient therapy to cure diabetic neuropathy. Diabetic neuropathy shows declined vascularity in peripheral nerves and lack of angiogenic and neurotrophic factors. Mesenchymal stem cells (MSCs) have been indicated as a novel emerging regenerative therapy for diabetic neuropathy because of their multipotency. We will briefly review the pathogenesis of diabetic neuropathy, characteristic of MSCs, effects of MSC therapies for diabetic neuropathy and its related mechanisms.

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Novel Treatment for Pancreonecrosis Using Cord Blood and Cord Tissue

To conclude, the obtained results demonstrate the effectiveness of the  cryopreserved umbilical cord blood TNCs (Pancrostem) as part of the complex treatment of patients suffering from necrotic pancreatitis. The were no immune or allergic reactions registered. The use of the cell therapy significantly decreased the frequency of postoperative complications, improved overall survival, and hastened the recovery of patients with this difficult and often fatal condition.

 

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Stem Cells: The Miraculous Blood In Your Baby’s Umbilical Cord

The stored stem cells aren’t just reserved for your baby and can be used for other siblings or close family members. This is because cord blood doesn’t require perfect matching, which means you have more donor options should you require them.
There is no question that my husband and I are storing these stem cells to ensure we are giving our child the best possible start in life by having a backup plan to mitigate health issues in the unfortunate event illness strikes.

 

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3 emerging innovations for blood vessel repair

MedCity News has partnered with BioCrossroads to provide coverage focused on Indiana’s next generation of growth and innovation in life sciences.

 

Different new technologies continue to emerge with the hope of improving blood vessel repair and replacement for those with various diseases, either with the help of stem cells, 3D printing or the use of other human cells to develop actual new tissue. One disease in particular is peripheral arterial disease.

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Artificial Skin Grown From Umbilical Cord Stem Cells: 'Wharton Jelly' Mesenschymal Could Transform Trauma Care, Burn Treatment

Although artificial skin may sound like science fiction, it could soon become a routine component of clinical practice and trauma care. In a new study, researchers from the University of Granada describe a new, groundbreaking method of generating artificial skin from stem cells derived from umbilical cord tissue. Aside from making open wounds a cinch to patch up, the innovative method could transform treatment and rehabilitation for burn victims.

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Cameron Clokie Talks Up The Potential of Regenerative Medicine in Canada

Technology amazes us in many ways. These days, the medical technology has exceeded the expectations of people and continuously keep on overwhelming us in different ways. Regenerative medicine is one of the latest technology in the medical field that aims at regeneration, repair, or replacing damaged organs and tissue. CEO of Induce BiologicsCameron Clokie takes a look at what makes this cutting edge field interesting.

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Can a stem cell injection unblock furred-up arteries? A simple jab may prevent pain while walking, ulcers and the need for amputation

A jab of stem cells could help prevent pain while walking, ulcers and the need for amputation in patients with furred-up arteries in the leg. Now, researchers in Canada, South Korea and Malaysia are investigating the use of stem cells to help ease PAD.
In many tissues, stem cells serve as a sort of internal repair system, dividing constantly to replenish cells that might be damaged. Results from a pilot study with 22 patients at Tehran University, Iran, show that those who were given the stem cell injections were able to walk further without pain after six months than those given placebo jabs.

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Clinical trial tests cord-blood cells to treat macular degeneration

"If the treatment is successful, that would mean that we might be able to use it in people with the beginning stages of dry age-related macular degeneration, when vision loss is not so severe, in order to slow the loss of RPE and photoreceptor cells," said Dr. Yannek Leiderman, assistant professor of ophthalmology in the UIC College of Medicine and lead surgeon in the clinical trial at UIC.

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Cord Blood Stem Cells Restore Toddler's Hearing

A virus infection Stephanie Connor acquired during pregnancy put her unborn daughter at significant risk for brain damage and lifelong hearing loss. "It was traumatic," said Connor, of LaBelle, Fl, after learning about her daughter's condition. "It was like mourning the loss of a child."...

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Cord Blood Therapy for Cerebral Palsy Shows Promise

“We are encouraged by the results of this study, which shows that appropriately dosed infusions of cord blood cells can help lessen symptoms in children with cerebral palsy,” said senior author Dr. Joanne Kurtzberg. She directs Duke University’s pediatric blood and marrow transplant program, in Durham, N.C.

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Could blood from babies’ umbilical cords rejuvenate our grandparents’ brains?

Even without diseases like Alzheimer’s and other dementia, human brains experience deterioration that inevitably comes with aging. One of the areas most affected is the hippocampus, a small region deep inside the brain that helps us remember our experiences. As we age, new cells aren’t as plentiful there, making it more difficult to remember and learn. Scientists hope that targeting this degeneration will help brains stay healthier longer. Mice suffer the same neurological consequences of aging. And in a new study, scientists at Stanford were able to reverse some signs of aging and improve memory and cognition using injections of umbilical cord blood from humans. 

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