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The treatment, is the first to reverse the symptoms of MS, which has no cure, and affects around 100,000 people in Britain.

By David Steenblock, M.S., D.O.

Multiple Sclerosis (MS) is an inflammatory, autoimmune, demyelinating disease of the central nervous system that destroys myelin, oligodendrocytes, and axons (14). Between 250,000 - 350,000 people in the United States alone suffer from Multiple Sclerosis.

BBC team follows MS patient Steven Storey's progress after the new treatment.

UK doctors in Sheffield say patients with multiple sclerosis (MS) are showing "remarkable" improvements after receiving a treatment usually used for cancer.

Review of “Association of Non-myeloablative Hematopoietic Stem Cell Transplantation with Neurological Disability in Patients With Relapsing-Remitting Multiple Sclerosis” from JAMA by Stuart P. Atkinson

Multiple sclerosis (MS) is a debilitating disease of the nervous system, associated with inflammation and damage of the myelin sheaths which protect nerve cells. Most patients require assistance to walk at 15 years or are unable to walk by 25 years, and at this time, no therapy exists which can reverse the neurological effects or improve quality of life.

ABSTRACT

Importance

Most patients with relapsing-remitting (RR) multiple sclerosis (MS) who receive approved disease-modifying therapies experience breakthrough disease and accumulate neurologic disability. High-dose immunosuppressive therapy (HDIT) with autologous hematopoietic cell transplant (HCT) may, in contrast, induce sustained remissions in early MS.

There are so many people interested in alternative treatments for multiple sclerosis, actually interested in anything that will improve our life style.

A great video featuring promise held by a new study from Case Western Reserve University on Adult Stem Cell treatment for Multiple Sclerosis.

Autologous stem cell transplant after immunosuppressive therapy induced 3 year remission in relapsing remitting multiple sclerosis patients

A new treatment for MS may stop the disease in its tracks in some patients. This high-dose therapy helped several MS patients.

A study of patients with relapsing-remitting multiple sclerosis (MS) found that many of those treated with high doses of medication to suppress their immune system (high-dose immunosuppressive therapy, or HDIT) plus a transplant of their own stem cells (hematopoietic cell transplant, or HCT) were disease-free several years later.

New research provides further evidence of autologous hematopoietic stem cell transplantation as an effective treatment for multiple sclerosis, after finding the procedure halted disease progression for 5 years in almost half of patients.
New research reveals that almost half of MS patients treated with AHSCT experienced no disease progression in the subsequent 5 years.
Lead study author Dr. Paolo Muraro, of the Department of Medicine at Imperial College London in the United Kingdom, and colleagues recently reported their findings in JAMA Neurology.The results come just a fortnight after another study revealed the success of a similar treatment in a small group of patients with relapsing-remitting multiple sclerosis (RRMS).

A novel Canadian treatment to halt the progression of multiple sclerosis (MS) is being hailed as revolutionary, after doctors and researchers used the new stem cell transplant method to treat the disease.

JAMA Neurology

Three years after a small number of patients with multiple sclerosis (MS) were treated with high-dose immunosuppressive therapy (HDIT) and then transplanted with their own hematopoietic stem cells, most of the patients sustained remission of active relapsing-remitting MS (RRMS) and had improvements in neurological function, according to a study published online by JAMA Neurology.

People with MS who were involved in a long-term clinical trial are out and about enjoying a full and normal life with no signs of the disease. This follows their recovery from the stem cell transplants involving aggressive chemotherapy, or aHSCT as the procedure is known.

For decades, physicians have relied on stem cell transplants to reset the immune system of patients who have hematologic cancers, such as leukemia and lymphoma. This has led researchers to wonder if stem cell transplants could also reset the immune system so that it would not attack the patient’s own body in autoimmune diseases, such as Multiple Sclerosis, Lupus, and Rheumatoid Arthritis. There are more than 80 types of autoimmune diseases.

BBC News

A 19-year-old MS sufferer has been able to walk for the first time in years after receiving stem-cell treatment. Amanda Bryson paid ?12,000 for injections in the Netherlands which she believes could cure her. Jackie O'Brien reports.

An experimental treatment that uses a patient's own stem cells may offer new hope for people with multiple sclerosis.

In a small clinical trial, patients experienced long-term disease remission after undergoing a transplant of their own hematopoietic stem cells. This type of cell is responsible for the formation of blood in the body and are typically derived from bone marrow. The patients also took high-dose immunosuppressive drugs.

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system.

A new use of chemotherapy followed by autologous haematopoietic stem cell transplantation (aHSCT) has fully halted clinical relapses and development of new brain lesions in 23 of 24 patients with multiple sclerosis (MS) for a prolonged period without the need for ongoing medication, according to a new phase 2 clinical trial, published in The Lancet.

Cell Adh Migr. 2013 Sep-Oct;7(5):404-7. doi: 10.4161/cam.26941. Epub 2013 Oct 30.

Abstract:

There is currently great interest in the use of mesenchymal stem cells as a therapy for multiple sclerosis with potential to both ameliorate inflammatory processes as well as improve regeneration and repair.

BBC News

A Wiltshire man with Multiple Sclerosis has agreed to trial a new stem cell treatment at Frenchay Hospital.